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. 2017 Apr 28;12(4):e0176702. doi: 10.1371/journal.pone.0176702

Fig 5. rtfA is necessary for normal resistance to oxidative stress.

Fig 5

(A) Sensitivity of A. fumigatus wild type (WT), ΔrtfA, complementation (com), and overexpression rtfA (OErtfA) strains to oxidative stress was examined on GMM containing various concentrations of menadione as indicated. Colony formation was observed after 72 h of incubation at 37°C. (B, C) In a separate experiment, the strains were inoculated in liquid GMM with or without 20 μM of menadione (men). Cultures were incubated at 30°C. Mycelia were collected 6 h after the shift for expression analysis of cat1 (B) and cat2 (C). Different letters above the bars indicate significantly different values (p ≤ 0.05). Error bars represent standard error.