Table 2. Clearance of implants pre-colonized with wild-type P. aeruginosa PAO1 inserted in the peritoneal cavities of BALB/c mice treated with various agents alone or in combination for 3 days.
Results are expressed as the mean ± standard deviation. *P<0.01 compared with the vehicle control group without baicalin treatment. &P<0.05 and ▲P<0.01 when the combination treatment group was compared with the antibiotic treatment alone.
| Group | Bacterial counts (Log10 CFU/implant) | |
|---|---|---|
| — Baicalin | + Baicalin | |
| Control | 6.24±0.66 | 5.38±0.50* |
| LEV | 5.22±0.42* | 4.46±0.61*▲ |
| AMK | 4.83±0.30* | 4.10±0.87*& |
| CAZ | 5.06±0.76* | 3.89±0.62*▲ |