Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Aug 18;25(20):4494–4506. doi: 10.1093/hmg/ddw278

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2016. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 4. — Muscle fibre cross-sectional area is reduced earlier in FVB Smn^2B/-mice than in BL6 Smn^2B/-mice. (A and B) Representative images of H&E stained TA muscles from BL6 mice (A) and FVB mice (B) at PND11 and PND16. (C and D) Quantification and analysis of myofibre cross-sectional areas showed that at PND11 there was no difference in the distribution of myofibres of BL6 Smn^2B/-mice (n = 3, two way ANOVA, P > 0.05). However, at PND11 there is a higher percentage of small caliber myofibres in FVB Smn^2B/-mice compared to their control littermates, and at PND16, the fractions of smaller myofibres are significantly higher in both BL6 and FVB Smn^2B/-mice (n = 3, two way ANOVA, P < 0.05). * indicates significant difference between Smn^2B/-mice and their control littermates.