Table 1.

Muscle fibre cross-sectional area is reduced earlier in FVB Smn^2B/- mice than in BL6 Smn^2B/- mice. Table shows the average myofibre cross-sectional areas in TA muscles at PND11 and PND16. At PND11 the average myofibre area was significantly reduced in FVB but not in BL6 Smn^2B/-mice. At PND16 both BL6 and FVB showed smaller myofibre cross-sectional areas (n = 3, Mann Whitney Test)

	PND11	Myofibre area		PND16	Myofibre area
FVB	Smn2B/-	509.7±139.2 µm2	P<0.0001	Smn2B/-	389.9±120 µm2	P<0.0001
	control	692±155.9 µm2		control	714.2±137 µm2
BL6	Smn2B/-	350±174.8 µm2	P>0.05	Smn2B/-	481.8±122.5 µm2	P<0.0001
	control	381.1±180.4 µm2		control	665.2±154.8 µm2