Table 1.

Genomic characteristics of primary AML specimens used for PDX model studies

PDX USI	Disease status	Leukemia cytogenetics and molecular lesions
AML290	De novo	46,XX,der(10)t(8;10)(q11.1;p15);13q LOH KMT2A partial tandem duplication
JMML117	De novo	45,XY,-7; PTPN11 G503V

Both AML specimens were CD52 negative by flow cytometry.

LOH, loss of heterozygosity; USI, unique specimen identifier.