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. Author manuscript; available in PMC: 2017 Apr 28.
Published in final edited form as: Lab Chip. 2013 Dec 7;13(23):4599–4607. doi: 10.1039/c3lc50802a

Fig. 5.

Fig. 5

Effects of myosin-II activation by calyculin A on traction forces of HOS cells. Plot of average traction force per post and distribution of traction forces per post for HOS cells migrating through (a) 50 × 4 μm2 or (b) 10 × 4 μm2 microchannels in the absence and presence of 0.1 nM calyculin A. For all experiments, micropost tops were coated with 50 μg ml−1 collagen type I. Data represent mean ± SEM from at least n = 20 posts. (c) Plot of average cell speed for control and calyculin A-treated (0.1 nM) HOS cells migrating through microchannels coated with 20 μg ml−1 collagen type I. *, P < 0.01 by one-way ANOVA followed by Tukey’s HSD post-test.