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. 2017 Apr 16;14(4):427. doi: 10.3390/ijerph14040427

Table 4.

Hazard ratio (HR) of all-cause mortality for invasive patients using stepwise Cox regression analysis.

Total UMSC UMMC Change in HR from Prior Model
Number of patients 3956 1193 2763
Number of deaths 1436 240 1196
Hazard ratio model A (95% CI) a 1 (ref) 2.22 (1.94–2.55)
Hazard ratio model B (95% CI) b 1 (ref) 2.06 (1.78–2.38) 7.21%
Hazard ratio model C (95% CI) c 1 (ref) 1.65 (1.43–1.91) 19.90%
Hazard ratio model D (95% CI) d 1 (ref) 1.59 (1.36–1.85) 3.64%

a Unadjusted hazard ratio; b Adjusted for age, ethnicity and year of diagnosis; c Adjusted for variables in model B plus tumor size (cm), number of regional nodes positive and distant metastasis (yes vs. no); d Adjusted for variables in model C plus locoregional treatment (no surgery, mastectomy only, mastectomy plus radiotherapy, breast conserving surgery only, breast conserving surgery plus radiotherapy), chemotherapy (no chemotherapy, 1st generation chemotherapy, 2nd generation chemotherapy, 3rd generation chemotherapy) and hormone therapy (no hormone therapy, hormone therapy).