Table 1.
Body weights (g) before and throughout pregnancy, and body composition and feto-placental unit near to term.
| Age/Pregnancy Stage | Gen0-C | Gen0-F | Gen1-C | Gen1-F |
|---|---|---|---|---|
| Body Weight (g) | ||||
| Week 8/Pre-diet | 200.6 ± 3.3 | 204.1 ± 3.1 | 225.1 ± 6.3 † | 226.4 ± 5.7 † |
| Week 9 | 227.0 ± 2.0 | 238.3 ± 2.9 | 254.5 ± 6.6 † | 252.3 ± 6.5 † |
| Week 10 | 247.3 ± 2.3 | 257.2 ± 3.1 | 280.7 ± 6.8 † | 285.9 ± 7.7 † |
| Week 11/Pre-mating | 261.5 ± 3.0 | 277.7 ± 4.7 | 305.5 ± 7.4 † | 316.3 ± 9.3 † |
| Week 12/ Early pregnancy | 290.5 ± 2.3 | 304.9 ± 5.3 | 332.2 ± 6.8 † | 352.3 ± 12.9 † |
| Week 13/ Mid pregnancy | 329.4 ± 5.1 | 337.6 ± 5.9 | 383.8 ± 7.6 † | 393.3 ± 14.3 † |
| Week 14/ Late pregnancy | 386.5 ± 5.4 | 403.1 ± 6.7 | 428.7 ± 12.3 † | 444.4 ± 15.6 † |
| Body Composition (%) | ||||
| Fat mass at GD21 | 11.2 ± 0.7 | 15.2 ± 1.0 * | 11.4 ± 0.5 | 16.7 ± 1.3 * |
| Feto-placental unit | ||||
| Number of pups | 15.5 ± 1.7 | 16.0 ± 3.2 | 16.3 ± 2.3 | 17.0 ± 3.3 |
| Placental weight (g) | 0.53 ± 0.02 | 0.48 ± 0.02 | 0.57 ± 0.02 | 0.47 ± 0.01 * |
| Fetal weight (g) | 3.88 ± 0.19 | 3.36 ± 0.14 * | 4.07 ± 0.05 | 3.57 ± 0.09 * |
| The ratio of placental:fetal weight | 0.14 ± 0.01 | 0.15 ± 0.01 | 0.14 ± 0.00 | 0.13 ± 0.01 |
All values are means ± SEM. Gen0-C n = 10, Gen0-F n = 10, Gen1-C n = 10, Gen1-F n = 10. * p < 0.05, Gen0-C vs. Gen0-F, or Gen1-C vs. Gen1-F (effect of diet) and † p < 0.05, Gen0-C vs. Gen1-C and Gen0-F vs. Gen1-F (effect of generation), unpaired t-test with a Bonferroni correction applied for multiple comparisons.