Table 4.
Twenty four hour SCFA excretion measured 38 and 81 days post rats arrival (µmol/24 h) in feces from rats treated with water (control) or DSS to induce colitis and consuming diets containing either cellulose or brans from Black, Sumac or Hi Tannin Black bran.1
| SCFA | Cellulose | Black Bran | Sumac Bran | Hi Tannin Black Bran | p-Value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Control | DSS | Control | DSS | Control | DSS | Control | DSS | Diet | DSS | Diet*DSS | ||
| Day 38 | Acetic | 43.01 ± 6.70 a | 32.55 ± 6.34 a,b,c | 29.63 ± 2.76 b,c | 26.95 ± 2.16 c | 32.52 ± 2.97 a,b,c | 39.96 ± 5.52 a,b | 28.52 ± 2.05 c | 25.94 ± 2.59 c | 0.0299 | ||
| Propionic | 8.72 ± 0.92 c | 7.85 ± 1.11 c | 11.78 ± 1.22 b | 11.27 ± 1.20 b,c | 18.53 ± 1.42 a | 17.60 ± 1.82 a | 13.64 ± 0.86 b | 12.41 ± 1.01 b | 0.0001 | |||
| Isobutyric | 1.44 ± 0.16 b | 1.35 ± 0.13 b | 1.49 ± 0.13 b | 1.48 ± 0.15 b | 2.91 ± 0.30 a | 2.82 ± 0.28 a | 3.16 ± 0.18 a | 3.02 ± 0.27 a | 0.0001 | |||
| Butyric | 13.34 ± 2.54 a,b | 12.79 ± 2.30 a,b | 16.13 ± 1.17 a | 14.36 ± 1.08 a,b | 8.15 ± 0.77 c | 8.18 ± 0.63 c | 12.99 ± 0.85 ab | 11.84 ± 1.16 b,c | 0.0001 | |||
| Isovaleric | 2.89 ± 0.39 b | 2.74 ± 0.28 b | 3.70 ± 0.31 b | 3.65 ± 0.36 b | 7.73 ± 0.81 a | 7.49 ± 0.81 a | 8.46 ± 0.50 a | 8.18 ± 0.78 a | 0.0001 | |||
| Valeric | 4.40 ± 0.40 b | 4.17 ± 0.48 b | 5.60 ± 0.70 b | 5.55 ± 1.04 b | 1.75 ± 0.96 b | 1.50 ± 0.73 b | 8.39 ± 0.99 b | 16.52 ± 7.90 a | 0.0035 | |||
| Total | 73.80 ± 9.62 a | 61.46 ± 9.35 a | 68.33 ± 5.81 a | 63.26 ± 5.52 a | 71.59 ± 4.67 a | 81.32 ± 7.49 a | 75.16 ± 3.67 a | 77.90 ± 8.97 a | ||||
| Day 81 | Acetic | 49.19 ± 6.70 a | 48.45 ± 6.33 a | 26.04 ± 2.76 b | 33.71 ± 2.17 a,b | 40.33 ± 2.98 a,b | 50.24 ± 5.52 a | 51.30 ± 2.05 b | 37.20 ± 2.59 a,b | |||
| Propionic | 10.79 ± 0.92 b | 12.59 ± 1.11 a,b | 9.10 ± 1.22 b | 22.43 ± 1.20 a | 22.40 ± 1.42 a | 23.98 ± 1.82 a | 22.06 ± 0.86 a | 17.14 ± 1.01 a,b | 0.0550 | |||
| Isobutyric | 1.52 ± 0.16 c | 1.53 ± 0.13 c | 1.14 ± 0.13 c | 1.54 ± 0.15 c | 3.75 ± 0.30 b | 3.77 ± 0.28 b | 5.85 ± 0.18 a | 4.53 ± 0.27 a,b | 0.0001 | |||
| Butyric | 19.67 ± 2.54 a | 16.45 ± 2.30 a,b | 15.98 ± 1.17 a,b | 20.07 ± 1.08 a | 9.20 ± 0.77 b | 8.80 ± 0.63 b | 20.24 ± 0.85 a | 14.08 ± 1.16 a,b | 0.0065 | |||
| Isovaleric | 2.83 ± 0.39 c | 2.94 ± 0.28 c | 2.99 ± 0.31 c | 3.78 ± 0.36 c | 9.48 ± 0.81 b | 9.28 ± 0.58 b | 14.91 ± 0.50 a | 11.35 ± 0.78 a,b | 0.0001 | |||
| Valeric | 4.17 ± 0.40 b | 4.46 ± 0.48 b | 3.98 ± 0.70 b | 5.04 ± 1.04 b | 0.71 ± 0.96 b | 0.55 ± 0.73 b | 14.39 ± 0.99 a | 12.11 ± 7.90 a | 0.0001 | |||
| Total | 88.08 ± 9.62 a,b | 86.41 ± 9.35 a,b | 59.22 ± 5.81 a | 86.55 ± 5.53 a,b | 85.88 ± 4.67 a,b | 96.61 ± 7.48 a,b | 128.74 ± 3.67 a | 96.41 ± 8.97 a,b | ||||
1 Values are least square means ± standard error of the mean. DSS = dextran sodium sulfate, Diet*DSS = Diet and DSS interaction. a,b,c Means in a row without a common superscript differ (p < 0.05).