Figure 3.

Effects of Hcy on hepatic lipogenesis. (a) Oil Red O staining of cultured primary hepatocytes treated with methionine or Hcy; (b) Protein expression of nSREBP1c in the liver; (c) Relative expression of genes involved in hepatic lipogenesis. The data are presented as mean ± SD. * p < 0.05, ** p < 0.015, and *** p < 0.001 vs. CT. FAS: fatty acid synthase; ACC1α: acetyl-CoA carboxylase 1α; HMG-COAr: hydroxymethylglutaryl CoA reductase; IPPi: isopentenylpyrophosphate isomerase; FPPs: farnesyl diphosphate synthase.