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. 2017 Apr 20;9(4):403. doi: 10.3390/nu9040403

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Figure A3 — Effect of genistein on SIRT1 mRNA expression following I/R injury. In the sham group, mice received the same volume of vehicle without I/R; in the I/R group, mice received the same volume of vehicle with I/R; in the G5 group, mice were pre-treated with 5 mg/kg genistein following I/R; in the G10 group, mice were pre-treated with 10 mg/kg genistein following I/R; in the G15 group, mice were treated with 15 mg/kg genistein. The mice were decapitated at 24 h of the reperfusion period for further analysis. The data were expressed as the mean ± SEM; n = 6; * p < 0.05 vs. Sham; ^# p < 0.05 vs. I/R. The SIRT1 mRNA levels for specific genes were normalized to 18S rRNA levels.