Figure A4.

Sirtinol reverses the effect of genistein on apoptosis in I/R-induced acute renal injury. Mice were treated as described in supplemental Figure 4. The data were expressed as the mean ± SEM; n = 6; * p < 0.05 vs. Vehicle; ^# p < 0.05 vs. G15. (A) Representative photomicrograph of cleaved caspase-3-stained kidney tissues from the G15 and G15 + Sirtinol groups. Original magnification, 400×; (B) Cleaved caspase-3-positive cells were counted, and the percentage of positive cells is illustrated. The black arrows indicate positive cells.