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The running distance in the mice fed a SD or HFD and subjected to voluntary exercise. Note that the animals were initially fed a SD and HFD over the period of 12 weeks and subsequently subjected to voluntary exercise for a period of six weeks. Results are mean ± S.E.M. of eight animals per each group. An asterisk indicates a significant change as compared to the respective values in sedentary exercising mice fed a SD (p < 0.05, t-test).
