Figure 8.
The plasma levels of TNF-α, MCP-1, IL-6 and IL-13 in sedentary mice with colitis fed a standard diet (SD) or high-fat diet (HFD) with or without voluntary exercise (Volunt). Please note the inhibitory effect of voluntary exercise on the proinflammatory biomarkers observed in the HFD mice with colitis. Results are mean ± S.E.M. of eight mice per each group. An asterisk indicates a significant difference as compared to the control groups of animals without colitis (p < 0.05, ANOVA). An asterisk and a cross indicate a significant difference as compared to the values obtained in rats fed a SD (p < 0.05, ANOVA). A cross indicates a significant difference as compared to the values obtained in the sedentary mice without colitis fed a HFD (p < 0.05, ANOVA). A double cross indicates a significant change as compared to the HFD mice without voluntary exercise (p < 0.05, ANOVA).