Table 1. Criteria for diagnosis of breast implant-associated anaplastic large cell lymphoma.

A tumor with adequate pathological specimen for analysis, involving an effusion either surrounding a breast implant lining a breast implant capsule

Neoplasm with large lymphoid cells with abundant cytoplasm and pleomorphic nuclei

Tumor demonstrates T-cell markers with uniform expression of CD30 by immunohistochemistry or flow cytometry

Negative for anaplastic lymphoma kinase (ALK) protein or translocations involving the ALK gene at chromosome 2q23