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. Author manuscript; available in PMC: 2017 May 19.
Published in final edited form as: FASEB J. 2007 Sep 10;22(2):418–427. doi: 10.1096/fj.07-9209com

Figure 2. 5-HT2BR−/− mice display decreased BMD that worsens with aging.

Figure 2

BMD was determined for the whole body (A) and femurs (B) of 5HT2BR−/− and wild-type (WT) female mice at the times indicated (n=5 per group). ANOVA for repeated measures revealed a statistically significant change related to genotype over time for both whole body and femoral BMDs (p < 0.05). BMD was also evaluated in 4- and 18-month-old 5-HT2BR−/− and WT mice (n = 15 to 20 per group) for the whole body (C) and the femur (D). Radiographies were performed on the femurs (E). *: significant (p < 0.05) difference between BMDs of 5-HT2BR−/− and WT mice. Mean values ± SEM (bars) are shown.