Fig. 6.

Searching for de novo mutations in a trio. Q1: to set the criteria the user should select “Shared variants” and click the box beside each patient, selecting green, red or gray respectively for present, absent and ignore, while the sentence underneath will report in plain English the meaning of the settings; more criteria can be set by clicking the + symbol. Q3: the results include haplotype phasing. The yellow bar indicated by the arrow is a possible de novo mutation. For the meaning of other symbols see Fig. 3