Table 2.
Zeta potential (ZP) of RICK, CADY-K and d-cady-k
| ID | ZP (mV) | ||
|---|---|---|---|
| 5% glucosea | OptiMEM | DMEM | |
| RICK | 40 ± 2 | 14 ± 3 | 14 ± 1 |
| CADY-K | 38 ± 1 | 13 ± 1 | 12 ± 3 |
| d-Cady-k | 40 ± 1 | n.d. | n.d. |
All CPP:siRNA complexes were formed at R = 20 using a siRNA concentration of 500 nM in an aqueous solution of 5% glucose, OptiMEM or DMEM
a For zeta potential (ZP) assessment the solution was supplemented with 5 mM NaCl (OptiMEM and DMEM contained NaCl)