Table 2.
Rescue strategies for intraoperative hypoxemia
| Lower PEEP | Higher PEEP | |||||
|---|---|---|---|---|---|---|
| Step | FiO2 | PEEP (cmH2O) | FiO2 | PEEP (cmH2O) | ||
| 1 | 0.5 | 4 | 0.4 | 14 | (+RM) | |
| 2 | 0.6 | 4 | 0.4 | 16 | (+RM) | |
| 3 | 0.7 | 4 | 0.4 | 18 | (+RM) | |
| 4 | 0.8 | 4 | 0.5 | 18 | ||
| 5 | 0.9 | 4 | 0.6 | 18 | ||
| 6 | 1.0 | 4 | 0.7 | 18 | ||
| 7 | 1.0 | 5 | 0.8 | 18 | ||
| 8 | 1.0 | 6 | 0.9 | 18 | ||
| 9 | 1.0 | 7 | (+RM) | 1.0 | 18 | |
| 10 | 1.0 | 20 | (+RM) | |||
Abbreviations: FiO 2 Fraction of inspired oxygen, PEEP Positive end-expiratory pressure, RM Recruitment maneuver
If intraoperative hypoxemia, defined as oxygen saturation ≤92%, develops, sequences of interventions will be used according to group assignment