Table 3.

The means of subjective discomfort grading, corneal erosion grading, Schirmer test and tear break up time (TBUT) between Group 1 and 2

	Group 1 (Taflotan-S® → Taflotan®)							Group 2 (Taflotan® → Taflotan-S®)
	start	1 month	3 month	6 month	7 month	9 month	12 month	start	1 month	3 month	6 month	7 month	9 month	12 month
Subjective discomfort (points)	0.70 ± 0.67	1.87 ± 1.24 p = 0.02*	1.11 ± 1.16 p = 0.31*	0.80 ± 1.39 p = 0.91*	0.50 ± 0.83 p > 0.99* p = 0.31†	0.25 ± 0.46 p > 0.99* p = 0.10†	0.60 ± 0.89 p = 0.78* p > 0.99†	1.33 ± 1.00	1.55 ± 1.66 p = 0.34*	1.85 ± 1.95 p = 0.26*	1.14 ± 0.69 p = 0.24*	1.60 ± 2.07 p = 0.10* p = 0.56†	1.28 ± 1.38 p = 0.11* p = 0.65†	0.87 ± 1.72 p = 0.08* p = 0.03†
Cornea erosion (points)	0.30 ± 0.48	0.25 ± 0.46 p = 0.56*	0.22 ± 0.44 p = 0.56*	0.40 ± 0.51 p = 0.56*	0.50 ± 0.54 p = 0.56* p > 0.99†	0.50 ± 0.53 p = 0.31* p = 0.65†	0.60 ± 0.54 p = 0.31* p = 0.56†	0.55 ± 0.52	0.33 ± 0.50 p = 0.15*	0.28 ± 0.48 p = 0.08*	0.14 ± 0.37 p = 0.15*	0.80 ± 0.83 p > 0.99* p = 0.15†	0.42 ± 0.53 p = 0.56 p > 0.99†	0.25 ± 0.46 p = 0.18* p > 0.99†
Schirmer (mm)	5.80 ± 3.88	2.62 ± 2.87 p = 0.20*	4.22 ± 3.15 p = 0.34*	4.60 ± 3.97 p = 0.40*	4.83 ± 6.27 p = 0.34* p = 0.58†	5.37 ± 6.04 p = 0.93* p = 0.68†	4.60 ± 4.56 p = 0.34* p = 0.78†	3.33 ± 3.04	5.66 ± 7.01 p = 0.88*	5.28 ± 3.40 p = 0.22*	5.14 ± 3.67 p = 0.40*	4.40 ± 1.34 p = 0.46* p = 0.70†	6.85 ± 5.04 p = 0.10* p = 0.25†	5.00 ± 3.02 p = 0.23* p = 0.73†
TBUT (sec)	5.80 ± 2.39	3.25 ± 1.28 p = 0.03*	4.33 ± 1.93 p = 0.23*	5.00 ± 1.88 p = 0.32*	4.83 ± 1.16 p = 0.28* p = 0.71†	5.00 ± 2.72 p = 0.73* p = 0.93†	3.60 ± 2.07 p = 0.06* p = 0.85†	4.55 ± 2.18	5.44 ± 2.29 p = 0.16*	5.00 ± 2.23 p = 0.14*	4.42 ± 1.71 p = 0.71*	3.60 ± 0.89 p = 0.15* p = 0.31†	4.14 ± 1.06 p = 0.67* p = 0.48†	4.75 ± 1.83 p = 0.60* p = 0.52†

*comparisons with before using tafloprost (start)

^†comparisions with the 6 months, in other words, before changing medication