Table 3. Summary of all data from sheep brain samples and transmissions to WT and transgenic mice (tg338), and conclusions on strain typing.

Summary of data from three WT mouse lines abstracted from Table 1. Incubation period (VL, very long; L, long; M, medium; S, short) and IHC designations are as defined in text. Western blot data represent lowest molecular mass (kDa) of PrP^Sc labelled by either of the antibodies 6H4 or P4. Attack rate is as defined in Tables 1 and 2. nd, Not done; na, not applicable; X, nothing labelled on the Western blot.

Inoculum	Sheep, source of inoculum			WT mice, three lines		tg338 mice						Conclusion on strain type
	IHC	Western blots: lowest-molecular-mass band (kDa)		Attack rate (%)	Incubation period	Attack rate (%)	Incubation period	Vacuolation profile type	IHC type	Western blots: lowest-molecular-mass band (kDa)
		6H4	P4							6H4	P4
Classical scrapie: 68 × 81(WT mice) and 47 × 79 (tg338)	Classical scrapie	21	21	0–39	VL	100	VL	B1	B1	21	21	Classical (1)
SSBP/1	Classical scrapie	21	21	50–100	VL	100	S	B2	I	21	21	Classical (2)
CH1641 (J2916)	Classical scrapie	19	X	17–39	VL	100	M	B1	I	19	21	Classical (3)
Scr2	Atypical scrapie	X	7–9	0	na	91	M	A	A	X	7–9	Atypical
51 × 45	Atypical scrapie	X	7–9	0	na	92	M	A	A	X	7–9	Atypical
L4824	Atypical scrapie	21	7–9	nd	na	91	M	A	A	X	7–9	Atypical
L4823	Classical scrapie	21	21	nd	na	18	L	A+B1	A+B1	21	7–9	Mixed atypical and classical (1)
H800	nd	21	∼8	nd	na	45	L	B1	B1	21	21	Classical (1)
13 × 85	nd	21	7–9	100	L	45	M	Mixed, A+another strain: B1 and/or B2	A+I	21	7–9	Mixed atypical and classical (2/3)