Table 2.
The Effect of Zinc Acetate Lozenges on the Rate of Recovery From the Common Cold in the 3 Included Trials
Trials | No. of Participants | Mean Duration of Colds in the Placebo Group (Days) | Effect of Zinc Lozenges on the Rate of Recovery | |
---|---|---|---|---|
RR | 95% CI | |||
Petrus et al [11] | 101 | 7.1 | 1.77 | 1.16–2.7 |
Prasad et al [12] | 48 | 8.1 | 7.5 | 3.5–16 |
Prasad et al [13] | 50 | 7.1 | 22 | 7.7–64 |
The 3 Trials Pooled | ||||
Cox model: study as a random effect | 199 | 3.1 | 2.1–4.7 | |
Cox model: stratified by study | 199 | 3.6 | 2.5–5.1 | |
Cox model: study ignored as a clustering variable | 199 | 2.6 | 1.9–3.5 |
Abbreviations: CI, confidence interval; RR, rate ratio.