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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Gen Comp Endocrinol. 2017 Jan 19;247:74–86. doi: 10.1016/j.ygcen.2017.01.019

Figure 7. Enrichment map analysis using conserved 283 up-regulated and 378 down- regulated genes shared between zebrafish and mammals (human and/or mice) during ovulation (p<0.0005).

Figure 7

A. Up-regulated biological processes during ovulation which include: transmembrane transportation, protein kinases, MAPK/JNK cascades, angiogenesis, the inflammatory response, cytokine production, cell migration, chemotaxis, extracellular matrix organization, cell growth, and cytoskeleton reorganization. B. Down-regulated biological processes during ovulation include: Pyrimidine metabolism, DNA repair, DNA methylation, DNA binding, DNA replication, cell cycle checkpoints, oocyte meiosis, chromatin modification, and cell phase transition.