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Left ventricular hemodynamics of cKO-CON and cKO-TAM mice at 14 days after tamoxifen treatment.
| LV Hemodynamics | cKO-CON (n=5) | cKO-TAM (n=7) |
|---|---|---|
| Peak systolic pressure (mmHg) | 95±9 | 72±4 * |
| End diastolic pressure (mmHg) | 5.2±3 | 12.5±4.8 * |
| Max dP/dt (mmHg/sec) | 10202±1227 | 6271±2262 * |
| Cardiac output (uL/min) | 6742±1457 | 8818±1052 * |
| Effective arterial elastance (mmHg/mL) | 7.6±1.7 | 3.9±0.6 * |
| Heart rate (beats per minute) | 528±27 | 497±12 |
