Lemieux et al. [11] |
6 |
553 |
1 |
87 |
69 |
19.478 |
64 |
4.498 |
First time breast cancer patients. Study undertaken in Canada. Mainly T1 and T2 tumor size; stage 1 & 2, treated with mainly cyclophosphamides and doxorubicin |
Parker [14] |
0 |
6 |
|
|
12 |
0.037 |
|
|
Stage 4 recurrent disease. Treated with IV CMF (2 cycles) |
Protiere et al. [18] |
0 |
77 |
0 |
109 |
44 |
1.729 |
|
|
First time breast cancer patients. 4 cycles of adjuvant IV chemotherapy with mitoxantrone + cyclophosphamide. Antiemetics also administered. Study undertaken in France |
Ridderheim [15] |
0 |
3 |
|
|
15 |
0.023 |
|
|
Adjuvant treatment breast cancer |
Ron et al. [19] |
0 |
19 |
0 |
16 |
14 |
0.136 |
14 |
0.181 |
Breast cancer patients treated with cyclophosphamide, methotrexate, and 5- fluorouracil [CMF]; unclear as to stage of breast cancer |
Rugo [17] |
0 |
101 |
|
|
29.5 |
1.521 |
|
|
Early-stage breast cancer patients |
Spaëth et al. [20] |
3 |
770 |
0 |
141 |
36 |
14.150 |
36 |
4.100 |
93% breast cancer patients. Treated with IV chemo mainly anthracyclines and/or taxotere. Unclear as to stage of breast cancer |
Tollenaar et al. [35] |
0 |
35 |
|
|
46 |
0.822 |
|
|
Patients treated with cyclophosphamide + doxorubicin + 5-fluorouracil on first operative day (one course of treatment). Unclear as to stage of cancer |
van de Sande [12] |
|
|
4 |
885 |
|
|
110 |
78.635 |
Stage 4 + lymph nodes |
van den Hurk et al. [13] |
3 |
395 |
|
|
26 |
5.242 |
|
|
treated with CMF; unclear as to stage of breast cancer |
Totals |
12 |
1959 |
5 |
1238 |
|
|
|
|
|
Averages |
|
|
|
|
32.39 |
43.14 |
56 |
87.41 |
|