Table 2.
MIC (µg/mL), MBC (µg/mL) of 3a, 3b, 3c, and 3d derivatives towards reference gram-positive bacterial strains
| Microorganisms | 3a | 3b | 3c | 3d | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MIC (µg/mL) | MBC (µg/mL) | MBC/MIC ratio | MIC (µg/mL) | MBC (µg/mL) | MBC/MIC ratio | MIC (µg/mL) | MBC (µg/mL) | MBC/MIC ratio | MIC (µg/mL) | MBC (µg/mL) | MBC/MIC ratio | |
| S. aureus ATCC6538 | 250 | 1000 | 4 | 31.25 | >1000 | >32 | 62.5 | 1000 | 16 | 31.25 | >1000 | >32 |
| S. aureus ATCC25923 | 125 | >1000 | >8 | 31.25 | 1000 | 32 | 31.25 | >1000 | >32 | 15.6 | >1000 | >64 |
| S. epidermidis ATCC12228 | 125 | 1000 | 8 | 31.25 | >1000 | >32 | 31.25 | 1000 | 32 | 31.25 | >1000 | >32 |
| M. luteus ATCC10240 | 125 | >1000 | >8 | 15.6 | 62.5 | 4 | 62.5 | >1000 | >16 | 15.6 | >1000 | >64 |
| B. subtilis ATCC6633 | 62.5 | 250 | 4 | 15.6 | >1000 | >64 | 15.6 | 62.5 | 4 | 7.8 | 500 | 64 |
| B. cereus ATCC10876 | 62.5 | >1000 | 16 | 125 | >1000 | >4 | 15.6 | >1000 | >64 | 7.8 | >1000 | >128 |
| S. pyogenes ATCC19615 | 250 | >1000 | >4 | 125 | 125 | 1 | 125 | >1000 | >4 | 250 | 500 | 2 |
| S. pneumoniae ATCC49619 | 125 | 250 | 2 | 500 | >1000 | >2 | 125 | 500 | 4 | 250 | 500 | 2 |
| S. mutans ATCC25175 | 250 | >1000 | >4 | 500 | >1000 | >2 | 500 | >1000 | >2 | 1000 | >1000 | Nd |