Table 3.
MIC (µg/mL), MBC (µg/mL) of 4a, 4b, and 4c derivatives towards reference gram-positive bacterial strains
| Microorganisms | 4a | 4b | 4c | ||||||
|---|---|---|---|---|---|---|---|---|---|
| MIC (µg/mL) | MBC (µg/mL) | MBC/MIC ratio | MIC (µg/mL) | MBC (µg/mL) | MBC/MIC ratio | MIC (µg/mL) | MBC (µg/mL) | MBC/MIC ratio | |
| S. aureus ATCC6538 | 7.8 | 15.6 | 2 | 3.9 | >1000 | >256 | 3.9 | >1000 | >256 |
| S. aureus ATCC25923 | 3.9 | 62.5 | 16 | 3.9 | >1000 | >256 | 3.9 | >1000 | >256 |
| S. epidermidis ATCC12228 | 3.9 | 62.5 | 16 | 3.9 | 7.8 | 2 | 3.9 | >1000 | >256 |
| M. luteus ATCC10240 | 3.9 | 125 | 32 | 3.9 | 7.8 | 2 | 3.9 | >1000 | >256 |
| B. subtilis ATCC6633 | 3.9 | 3.9 | 1 | 1.95 | 3.9 | 2 | 1.95 | 3.9 | 2 |
| B. cereus ATCC10876 | 3.9 | 125 | 32 | 3.9 | 3.9 | 1 | 3.9 | 3.9 | 1 |
| S. pyogenes ATCC19615 | 125 | >1000 | >8 | 125 | 500 | 4 | 500 | >1000 | Nd |
| S. pneumoniae ATCC49619 | 125 | 500 | 4 | 125 | 500 | 4 | 500 | 1000 | 2 |
| S. mutans ATCC25175 | >1000 | >1000 | Nd | 1000 | >1000 | Nd | 1000 | >1000 | Nd |