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. 2017 Mar 8;8(14):22353–22360. doi: 10.18632/oncotarget.16023

Figure 4. Graphic depiction of PR, Wnt4 and Versican expression between different subgroups.

Figure 4

Group 1&2: nulliparous women, Group 3&4: women with a full term pregnancy before the age of 30 years (early pregnancy), Group 5&6: women with a full term pregnancy after the age of 30 years (late pregnancy), Group 2: nulliparous women with subsequent breast cancer, Group 4: women with early pregnancy and no subsequent breast cancer. a. significantly lower numbers of PR+ epithelial cells in nulliparous women without subsequent breast cancer (Group 1) compared to nulliparous women with subsequent breast cancer (Group 2) b. significantly lower numbers of PR+ epithelial cells in women with early pregnancy and no subsequent breast cancer (Group 4) compared to nulliparous women with subsequent breast cancer (Group 2) c. significantly lower numbers of Wnt4+ epithelial cells in women with early pregnancy compared to nulliparous women. d. significantly lower numbers of Wnt4+ epithelial cells in women with late pregnancy compared to nulliparous women e. significantly higher number of Wnt4+ cells in nulliparous women with subsequent cancer (Group 2) when compared to the late pregnancy group without subsequent breast cancer (Group 6) f. significantly lower Versican expression in epithelial cells in women with early pregnancy (Group 1&2) compared to women with late pregnancy (Group 5&6).