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. 2017 Feb 8;8(14):22716–22729. doi: 10.18632/oncotarget.15187

Figure 4. The effect of anti-human IL11Rα antibody combination treatment with doxorubicin on AN3CA xenograft tumour growth in vivo.

Figure 4

(A, B) Female Balb/c athymic nude mice inoculated with 5 × 105 AN3CA cells on both hind flanks were administered with IgG control, IL11Rα Ab (200 μg per dose 3 times weekly) ± doxorubicin (5 mg/kg once), or doxorubicin alone and tumour volume calculated (n = 5 mice/group). (C) IL11, (D) GP130 and (E) IL11Rα gene expression was assessed in AN3CA tumours by quantitative real time RT-PCR. Data are mean ± SEM; ANOVA, *p < 0.05 (n = 5/group).