Table 2. TERT rs2736098 and 2736100 genotyping in healthy adults and HCC patients.
HA | HCC | Odds ratio (95% CI) | P value | |
---|---|---|---|---|
Genotype | ||||
rs2736098 (N) | 240 (100%) | 231 (100%) | ||
TT | 31 (12.9) | 19 (8.2) | 1.0 (ref.) | |
CT | 115 (47.9) | 127 (55.0) | 1.802 (0.965–3.364) | 0.088 |
CC | 94 (39.2) | 85 (36.8) | 1.475 (0.7763–2.804) | 0.303 |
CT + CC | 209 (87.1) | 212 (91.8) | 1.655 (0.906–3.023) | 0.133 |
CC | 94 (39.2) | 85 (36.8) | 1.0 (ref.) | |
TT + CT | 146 (60.8) | 146 (63.2) | 1.106 (0.762–1.605) | 0.664 |
rs2736100 (N) | 237 (100%) | 201 (100%) | ||
AA | 69 (29.1) | 74 (36.8) | 1.0 (ref.) | |
AC | 108 (45.6) | 92 (45.8) | 0.794 (0.517–1.221) | 0.347 |
CC | 60 (25.3) | 35 (17.4) | 0.544 (0.320–0.925) | 0.033 |
AC + CC | 168 (74.7) | 127 (63.2) | 0.705 (0.472–1.053) | 0.107 |
CC | 60 (25.3) | 35 (17.4) | 1.0 (ref.) | |
AA + AC | 177 (73.7) | 166 (82.6) | 1.608 (1.007–2.566) | 0.060 |
HCC, Hepatocellular carcinoma; CI, Confidence interval.