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. 2017 Feb 19;8(14):23130–23141. doi: 10.18632/oncotarget.15506

Figure 3. Detection of CTCs by using different methods.

Figure 3

We entitled the detected CTCs by CanPatrolTM, CytoploRare and Pep@MNPs, as EMT-CTCs, (FOLR)(+)-CTCs and EPCAM(+)-CTCs, respectively. (A) EMT-CTCs and FOLR(+)-CTCs were simultaneously detected prior to operation in cases C1-C5. EMT-CTCs were detectable in cases C1-C5, and FOLR(+)-CTCs were positive (FOLR value > 8.7 FU/3 ml) in cases C1, C3, C4 and C5. The size of balls represented the CTCs count or FOLR value. (B) EMT-CTCs and EPCAM(+)-CTCs were simultaneously detected prior to operation in cases D1-D3 E-CTCs were detectable in cases D1 and D2, and EpCAM(+)-CTCs were positive in cases D1–D3, suggesting Pep@MNPs probably is more capable of capturing epithelial CTCs.