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. 2017 Feb 19;8(14):23167–23176. doi: 10.18632/oncotarget.15517

Figure 2. Endo-siRNAs derived from porcine L1 retrotransposon.

Figure 2

(A) Analysis of high expressed endo-siRNAs in zygotes compared to sperms and oocytes; (B) Read counts of L1-siRNAs and their binding sites on L1 retrotransposon. L1-siRNAs derived from sense and antisense strands of L1 were marked by red and blue; (C) L1-siRNAs generated from a dsRNA formed between asL1 and L1 ORF2. LNA-asL1 and LNA-L1 are represented by red and grey bars, respectively. Arrowheads represent primers used in 5′ and 3′ RACE. The base mismatch was marked by red; (D) Effective knockdown of L1-siRNAs by LNA-asL1. Error bars represent s.d. (n = 3). * indicates p < 0.001.