Table 2. Performance values of different indexes for differentiation between AIS-MIA and IAC in solitary GGNs with stage IA lung cancer on PET/CT.
| Index | Threshold value | Sensitivity | Specificity | PPV | NPV | Accuracy |
|---|---|---|---|---|---|---|
| SUVmax | > 0.95 | 72.1 (31/43) | 86.7 (13/15) | 93.9 (31/33) | 52.0 (13/25) | 75.9 (44/58) |
| CTR | > 0.39 | 72.1 (31/43) | 86.7 (13/15) | 93.9 (31/33) | 52.0 (13/25) | 75.9 (44/58) |
| CTR + SUVmax + Nodule type† | > 0.38/> 1.46/mGGN | 95.3 (41/43)* | 60.0 (9/15) | 87.2 (41/47) | 81.8 (9/11) | 86.2 (50/58) |
Note.— Data are expressed as are percentages, with the numbers of solitary GGNs used to calculate the percentages in parentheses. GGN: ground-glass opacity nodule; SUVmax: maximum standard uptake value; PPV: positive predictive value; NPV: negative predictive value; CTR: consolidation/tumor ratio.
*Significant difference (p < 0.05) between sensitivity of the parameter and those of SUVmax > 0.95 and CTR > 0.39.
†Combination value means that either of three parameters is positive, then the diagnosis is positive.