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. 2017 Feb 21;8(14):23337–23352. doi: 10.18632/oncotarget.15578

Figure 3. Spy1-mediated ERK phosphorylation is MEK-independent.

Figure 3

(A–C) Hek-293 cells were infected (A) or transfected (B and C) with the indicated constructs (along top of each representative blot and X-axis of each graph. (A) Cells were treated with 10 μM U0126 or vehicle control (DMSO). (A–C) Representative blot (left). Densitometry (right) as represented on Y-axis or text box. Error bars reflect SE between at least 3 experiments. Student's t-test was performed; *p < 0.05, **p < 0.002, ***p < 0.001.