Table 3. The genotypes and allele frequencies of DNMT3A rs1550117 A>G in NSCLC patients.
Variables | Genotype | p value1 | Allele | p value2 | ||||
---|---|---|---|---|---|---|---|---|
GG | GA | AA | G | A | ||||
Total | 441 | 145 | 14 | 1027 | 173 | |||
Age | ≤ 60 | 246 | 76 | 8 | 0.768 | 568 | 92 | 0.603 |
> 60 | 195 | 69 | 6 | 459 | 81 | |||
Gender | Male | 312 | 107 | 9 | 0.656 | 731 | 125 | 0.607 |
Female | 129 | 38 | 5 | 296 | 48 | |||
Smoking status | Ever | 130 | 33 | 4 | 0.347 | 293 | 41 | 0.224 |
Never | 313 | 110 | 10 | 736 | 130 | |||
Alcohol status | Ever | 144 | 42 | 6 | 0.482 | 330 | 54 | 0.811 |
Never | 297 | 103 | 8 | 697 | 119 |
1 Two-sided χ2 test for genotype distribution.
2 Two-sided χ2 test for allele distribution.