Figure 6. Overexpression of HRD1 increased the sensitivity of drug-resistant breast tumors to Tamoxifen treatment in vivo.

MCF7/Tam cells stably overexpressing of HRD1 and the corresponding controls were injected into the right flank and left flank of nude mice, respectively. Tumor volume (A) and body weights of mice with tumors (B) were measured. *P < 0.05, compared to vector.