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. 2017 Feb 28;8(14):23702–23712. doi: 10.18632/oncotarget.15784

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Copyright: © 2017 Nytko et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) Residual γH2AX foci were analyzed in A549 cells treated for 4 hours with evofosfamide and irradiation with 2 Gy. Cells were analyzed 20 hours after irradiation at a magnification of 40x. (B) Induction of senescence (β-galactosidase staining) in response to the combined treatment in A549 cells. Cells were analyzed 72 hours after treatment at a magnification of 10x. At least 50 cells/condition were analyzed. Representative pictures are shown. Error bars represent SEM.