Table.
Clinical Characteristics of 4 Cases with Pulmonary Mucormycosis.
| Case no. |
Age / Sex |
Underlying disease |
Prior antifungal |
Documented DNA of Mucorale |
Chest CT imaging |
BG (pg/mL) |
GM index | Ferritin (ng/mL) |
DM | Neutropenia | Treatment | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 54/F | AML | VRCZ | Cunninghamella species | Small nodules, diffuse infiltration with thick wall | 12.8 | Negative | 3,110 | No | Yes | L-AmB | bDied of AML |
| a2 (1) | 48/M | AML | VRCZ | Rhizopus species | A small nodule | Negative | 5.0' | 3,500 | Yes | No | L-AmB | Improved |
| a2 (2) | 49/M | AML | VRCZ | Rhizopus species | Multiple small nodules | Negative | Negative | 3,550 | Yes | No | L-AmB | Improved |
| 3 | 67/M | NHL | VRCZ | Rhizopus species | Small nodules with reversed hallo sign | Negative | Negative | 1,080 | Yes | No | L-AmB | Improved |
| 4 | 20/F | AML | FLCZ→MCFG → VRCZ |
Absidia species | Multiple small nodules | 28.2 | Negative | 818 | No | Yes | L-AmB | Improved |
AML:acute myeloid leukemia, NHL: non-Hodgkin's lymphoma, VRCZ: voriconazole, FLCZ: fluconazole, MCFG: micafungin, CT: computed tomography, BG: (1-3)-β-D glucan, GM: galactomannan antigen, DM: diabetes mellitus, L-AmB: liposomal amphotericin B
aTwo episodes were included in case 2.
bThis case died of AML recurrence though mucormycosis was improved.