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SFN inhibited the increased expression of HDACs mRNA and protein in Aβ-treated SH-SY5Y cells. The relative expression of HDAC1, HDAC2 and HDAC3 mRNA (β-actin as a reference standard) (A) and protein (B,C) were analyzed by qRT-PCR and Western blot, respectively. (n = 6; mean ± SD; One-way ANOVA followed by LSD multiple comparison tests; *p < 0.05, **p < 0.01 vs. control group, #p < 0.05, ##p < 0.01 vs. SFN group, Δp < 0.01, ΔΔp < 0.01 vs. Aβ group).
