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. 2017 May 1;11:243. doi: 10.3389/fnins.2017.00243

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Copyright © 2017 Wang, Wang, Wu, Huang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Intraperitoneal injection of yohimbine potentiated elicited NE release signal in the CUMS rats. (A) Representative raw data of typical NE release signals recorded in the control rats before and after yohimbine. (B) Representative raw data of typical NE release signals recorded in the CUMS rats before and after yohimbine. (C) Yohimbine significantly increased the peak value of NE in the PVN of the CUMS rats, but no significant difference was observed in the control rats. (D) The ratio of increase in the peak value of NE signal was significantly amplified after administration of yohimbine in the CUMS rats compared to that in the control rats. The ratio: [(after-before)/before yohimbine]. ^**p < 0.01 vs. the control rats, ^##p < 0.01 vs. before yohimbine administration in the CUMS group. NS represents no significance.