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Cross‐reactive antibodies can be removed by serum adsorption without loss of subtype‐specific antibodies. Serum samples from persons who received ASO3‐adjuvanted split H5N1 vaccine were either mock or pH1/H3 rHA‐conjugated latex beads adsorbed. Pre‐ and post‐adsorption S2 sera were tested by MAGPIX (A) and DPP (B); post‐adsorption S1 and S2 sera were tested by MAGPIX (2C) and DPP (2D). For each group, the mean MFI/DPP value and ± the standard deviation are shown. *P<.05
