Table 1.
Serum source | Age range (yrs) | S1a | S2b | For sensitivityc | For cross‐reactivityd | |||||
---|---|---|---|---|---|---|---|---|---|---|
pH1 | H5 | H2 | H5 | H7 | H9 | H13 | ||||
H5N1 vaccineese | 30‐59 | 13 | 13 | N/A | 13 | 13 | N/A | 13 | 13 | 13 |
A(H1N1)pdm09 infected personsf | 19‐49 | 21 | 21 | 21 | N/A | 21 | 21 | 21 | 21 | 21 |
pH1N1 vaccineesg | 26‐64 | 15 | 15 | 15 | N/A | 15 | 15 | 15 | 15 | 15 |
Total number of specimens | 19‐64 | 49 | 49 | 36 | 13 | 49 | 36 | 49 | 49 | 49 |
Pre‐vaccination sera (S1) from vaccine studies or acute sera (S1) from A(H1N1)pdm09 virus‐infected persons were collected from US residents.
Post‐vaccination sera (S2) or convalescent (S2) showed HI ≥ 40, MN ≥ 80, and fourfold or greater rise in antibody titer, all sera collected from US residents.
Serum sample pairs were used to determine sensitivity by fold rises in MFI and DPP values for exposed antigens.
Serum sample pairs were used to determine cross‐reactivity by fold rises in MFI and DPP values for unexposed antigens.
Sera were collected from ASO3‐adjuvanted A/Indonesia/05/2005 (H5N1) vaccine study.
Sera were collected from pH1N1‐infected persons.
Sera were collected from split monovalent A/California/07/09 (pH1N1) vaccine study.