Table 3.
Serum source | Adsa | Sensitivityb | Cross‐reactivityc | Specificityd | |||
---|---|---|---|---|---|---|---|
MAGPIX | DPP | MAGPIX | DPP | MAGPIX | DPP | ||
Seroconversione | N | 83% (5/6) | 67% (4/6) | 0% (0/6) | 0% (0/6) | na | na |
Seroconversione | Y | 100% (6/6) | 83% (5/6) | 0% (0/6) | 0% (0/6) | na | na |
Seronegativesf | N | na | na | na | na | 100% (15/15) | 100% (15/15) |
Seronegativesf | Y | na | na | na | na | 100% (15/15) | 100% (15/15) |
Serum samples were either mock (N) or adsorbed (Y) with ectodomain pH1/H3 rHA‐conjugated latex beads.
Sensitivity was determined by the highest fold rise for H5 GH HA1 in MFI and DPP values (≥2 fold).
Cross‐reactivity was determined by the highest fold rise for unexposed antigens in MFI and DPP values (≥2 fold).
Specificity was determined by the highest fold rise for H5 GH HA1 in MFI and DPP values (≥2 fold).
Sera were collected from H5N1‐infected persons that showed seroconversion to A/BD/3233/2011 (H5N1) in MN.
Sera were collected from persons that showed seronegative to A/BD/3233/2011 (H5N1) in MN.