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. 2017 Apr;58(2):150–159. doi: 10.3325/cmj.2017.58.150

Table 1.

Half-maximal inhibitory concentration (IC50) determined in the cell viability and proliferation assay (MTT) assay and Trypan blue exclusion testing of human glioblastoma U251 cells treated for 24 h and 48 h with the Les-3288, doxorubicine (Dox), and temozolomide (TMZ)

IC50 μg/mL MTT assay
Trypan blue testing
24 h 48 h 24 h 48 h
Dox
0.96
0.41
0.88
0.13
Les-3288
0.74
0.31
0.63
0.22
TMZ 50.26 24.43 50.02 34.00