Figure 8. Nilotinib decreases the protein expression of HDACs 1, 2 and 4 in HSCs.
Effects of imatinib and nilotinib treatments for 24hr on the protein expression of HDACs 1, 2 and 4 as assessed by Western blotting for the total lysates of LX-2 cells. Data are means ± SE of at least 4 independent experiments. Statistically significant differences are indicated as: *P<0.05 and ***P<0.001 versus CTRL; +P<0.05 and +++P<0.001 versus imatinib (10 μM); ΔP<0.05 and ΔΔP<0.01 versus imatinib (20 μM).