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FMRFa competes with RPRFa. (Left) Representative current traces of homomeric ASIC3, activated with pH 6.3. RPRFa (30 μM; red bars) was preapplied at pH 7.4 for 30 s, either alone or together with 500 μM FMRFa. (Right) Quantification of currents 5 s after activation, normalized to the respective peak currents (n = 8). ***P < 0.001 (one-way repeated-measures ANOVA).
