Table 1.
Neutralization of HIV-1 isolate CH120.6 by known monoclonal antibodies
| Antibody | Neutralization titer | |||
| Epitope | Name | MPI, % | IC50, μg/mL | IC80, μg/mL |
| CD4bs | VRC01 | 95 | 11 | 25 |
| NIH45-46 | 92 | 8.8 | 35 | |
| 12A12 | 98 | 7.3 | 24 | |
| DH583 | 25 | >50 | >50 | |
| CD4i | 17b | 0 | >50 | >50 |
| 412d | 2 | >50 | >50 | |
| V1V2-glycan | PG9 | 64 | 18 | >50 |
| PG16 | 58 | 27 | >50 | |
| PGT145 | 96 | 0.75 | 3.8 | |
| V2 | 2158 | 0 | >50 | >50 |
| V3 | 3791 | 0 | >50 | >50 |
| 447-52D | 22 | >50 | >50 | |
| V3-glycan | PGT128 | 77 | 12 | >50 |
| 10-1074 | 100 | 0.27 | 0.70 | |
| Glycan | 2G12 | 14 | >50 | >50 |
| MPER | 4E10 | 54 | 47 | >50 |
| 10E8 | 99 | 4.4 | 15 | |
| Cluster I | 240-D | 7 | >50 | >50 |
| 246-D | 8 | >50 | >50 | |
| Cluster II | 1281 | 16 | >50 | >50 |
| PGT151 (IgG) | 45 | >50 | >50 | |