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. Author manuscript; available in PMC: 2018 May 4.
Published in final edited form as: Neuroscience. 2017 Feb 28;349:106–117. doi: 10.1016/j.neuroscience.2017.02.041

Figure 6. Pre-emptive DZNep or GSK126 treatment significantly attenuates the increased levels of EZH2 and H3K27TM in the spinal dorsal horn induced by nerve injury.

Figure 6

(A): Data were obtained from the spinal dorsal horn of animals treated with daily intrathecal injection of either 20 nM DZNep (in 10 μL) or vehicle (10 μL) for 9 days. (B): Data were obtained from the spinal dorsal horn of animals treated with daily intrathecal injection of either 5 nM GSK126 (in 10 μL) or vehicle (10 μL) for 9 days. Bar graphs show the mean (+ S.E.) relative density ratio of EZH2 over β-actin and H3K27TM over total-histone H3. Western blot samples of each molecular protein in each group are displayed. *p < 0.05; **p < 0.01; ***p < 0.001.