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. Author manuscript; available in PMC: 2018 May 4.
Published in final edited form as: Neuroscience. 2017 Feb 28;349:106–117. doi: 10.1016/j.neuroscience.2017.02.041

Figure 7. Pre-emptive treatment of the EZH2 inhibitor attenuates the increased expressions of Iba1, GFAP, TNF-α, IL-1β and MCP-1 in the spinal dorsal horn of rats with nerve injury.

Figure 7

Data were obtained from the spinal dorsal horn of animals treated with daily intrathecal injection of either 20 nM DZNep (in 10 μL) or vehicle (10 μL) for 9 days. Bar graphs show the mean (+ S.E.) density of GFAP, Iba1, TNF-α, IL-1β and MCP-1 relative to β-actin in the spinal dorsal horn of sham operated rats treated vehicle, pSNL rats treated with DEZNep, and pSNL rats treated vehicle. Samples of each molecular protein in each group are displayed. *p < 0.05; **p < 0.01.