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. 2017 May 1;12(5):e0176700. doi: 10.1371/journal.pone.0176700

Fig 6. Transcriptome expression profiles of selected genes involved in cholesterol biosynthesis and export in acute T. gondii infection.

Fig 6

Microarray data in brain and peripheral lymphocytes in infection with ME49 (type II) and RH (type I) parasites (data from Jia et al. [12]). RNa-seq data in liver in infection with PYS (type I/III) parasites (data from He et al. [14]). Panel A–extract from cholesterol biosynthetic pathway and export (adapted from KEGG pathways). Panel B–differential gene expression represented by fold change values / color for each microarray probe or gene: mouse brain in T. gondii type II / type I infection (ME_Br / RH_Br); mouse peripheral lymphocytes in T. gondii type II / type I infection (ME_PL / RH_PL); mouse liver in T. gondii strain PYS (type I/III). A–not identified as a differentially expressed gene in all three biological replicates.